7-11 July 2019
EV78 - CEL 7: How do we know they’re good? Design and Administration of a Bioassay Oversight Program (Rosenberg)Orlando VI 06:45 - 07:45 |
| Missing an occupational exposure can have dire consequences. It is the bioassay program’s responsibility to ensure quality in its measurements, both direct (in vivo) and indirect (in vitro), regardless of whether the measurements are performed in-house or through an offsite vendor. This presentation addresses how the DOELAP-accredited Hanford Internal Dosimetry Program oversees its direct and indirect bioassay programs. We will discuss some practices that have bolstered the program, allowing it to catch shortfalls that would have resulted in false positives and missed detections. Lessons learned include 1) the consequences of using synthetic versus real excreta samples, 2) the value of blind and double-blind quality control samples, and 3) the statistical power of recounts. |
