ASP Program by Session
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Advancing Light Therapy in the Clinical Setting
Chair: Gal Shafirstein
May 18 Afternoon Advancing Light Therapy in the Clinical Setting 3:15 – 3:35 Advances in photothermal therapy of hematological malignancies Johannes Zakrzewski 3:42 – 4:02 Photodynamic Therapy for Basal Cell Carcinoma in Clinical Practice Nathalie Zeitouni 4:09 – 4:29 Challenges and Opportunities in Treating Malignant Central Airway Obstruction with Interstitial Photodynamic Therapy Nathaniel Ivanick 4:36 – 4:56 An overview and a New Perspective on Light Dosimetry in Photodynamic Therapy Gal Shafirstein 5:03 – 5:15 Panel discussion
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Antimicrobial PDT Part 1
Chair: Janusz Dabrowski
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Antimicrobial PDT Part 2
Chair: Andres Durantini
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Bioenergy and Photosynthesis/Photoconversion
Chair: TBD
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Chemiexcitation in Mammalian Biology and Medicine
Chair: Doug Brash
May 17 Morning Chemiexcitation in Mammalian Biology and Medicine 10:05 – 10:20 Chemical excitation of electrons beyond skin & melanin: retina, hormones, neurotransmitters Douglas Brash 10:20 – 10:40 Melanin as a Redox Hub: From Light Absorption to Dark-Phase Photochemistry Sanjay Premi 10:45 – 11:00 Monitoring the triplet excited states of synthetic and natural melanins by application of diene probes with different electric charge Tadeusz Sarna
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Computational Photobiology / Quantum Computing in Photobiology
Chairs: Marta Alberto, Antonio Francés-Monerris
May 18 Afternoon Computational Photobiology / Quantum Computing in Photobiology 3:15 – 3:35 Computational Modelling of Light-Driven Mechanisms in Metal and Metal-Free Photosensitizers for Photodynamic Therapy Marta Erminia Alberto 3:35 – 3:55 Multiscale Modelling of Emergent Photoactivated Anticancer Therapies Antonio Francés-Monerris 3:55 – 4:15 Computational studies of potassium-selective channelrhodopsin Igor Schapiro 4:15 – 4:35 Quantum computing meets AI: a new frontier for virtual screening of photosensitizers and photocatalysts Stefan Knecht 4:35 – 4:55 Metal-Based Photosensitizers Design using Quantum Chemical Computational for Photodynamic Therapy Vijay Krishna 4:55 – 5:15 Moderated Discussion / Cross-Talk / Audience Q&A -
Dermato-Oncology: UV-Induced Skin Carcinogenesis Part 1
Chair: Masaoki Kawasumi
May 17 Morning Dermato-Oncology: UV-Induced Skin Carcinogenesis Part 1 10:05 – 10:35 Glutamatergic signaling in acral/mucosal melanoma Suzie Chen 10:35 – 11:05 Immunoediting restricts clonal neoantigens in human cutaneous squamous cell carcinoma Karen Hastings 11:05 – 11:30 Coffee break 11:30 – 11:52 Epigenetic regulation of UV-induced photoaging: shared molecular pathways in skin carcinogenesis Dong Hun Lee 11:52 – 12:14 Identifying novel biomarkers for effective prevention of skin carcinogenesis Katie Dixon 12:14 – 12:36 Polo-like kinase 4 as a driver of cutaneous melanoma progression Nihal Ahmad 12:36 – 12:58 Transcriptional profiling of cutaneous squamous cell carcinoma reveals subtype-specific regulatory programs and therapeutic vulnerabilities Masaoki Kawasumi
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Dermato-Oncology: UV-Induced Skin Carcinogenesis Part 2
Chair: Masaoki Kawasumi
May 19 Afternoon Dermato-Oncology: UV-Induced Skin Carcinogenesis Part 2 3:15 – 3:39 Genome-wide maps of mutations and UV photoproducts induced by sunlight John Wyrick 3:39 – 4:03 Loss of CCAAT enhancer binding protein beta transcription factor primes the keratinocyte cGAS-STING response to UVB-induced DNA damage." Jonathan Hall 4:03 – 4:27 Protein tyrosine dephosphorylation signaling in the regulation of UVB-induced epidermal apoptosis Dae Kim 4:27 – 4:51 Immunosuppression by cyclosporine A accelerates melanoma initiation and progression in BRAFV600E/PTENNull mice Gagan Chhabra 4:51 – 5:15 RNA modifications in UV stress response and tumorigenesis Yu-Ying He
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ESP-ASP Joint Session: Photosensitization: a Tribute to Professor Miguel A. Miranda
Chairs: Santi Nonell, Sherri McFarland
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From Lab to Launch: Entrepreneurship in Photobiology Spotlight
Chairs: Shiyong Wu, Sumiao Pang
May 18 Morning From Lab to Launch: Entrepreneurship in Photobiology Spotlight 9:05 – 9:25 Acetyl Zingerone: A Multi-Pathway Skin Longevity Molecule Targeting AMPK, Nrf2, and the Matrisome Ratan Chaudhuri 9:25 – 9:45 Innovative Photoactivated Ruthenium Chemotherapy to treat eye cancer: the translational journey of a university researcher Sylvestre Bonnet 9:45 – 10:05 Advancing Porphyin-Phospholipid Technology Jonathan Lovell 10:30 – 10:50 Safety Evaluation and Regulatory Pathways for the Industrialization of Engineered Skin Probiotics Yong Han 10:50 – 11:10 Lyme Disease, Curly Horses, and Invasive Plants: Translating a Photoantimicrobial for Dental Applications Colin Cameron 11:10 – 11:30 My Multi‑Decade Entrepreneurial Journey in Playing with Light Sean Wang 11:30 – 11:50 AI-assisted evaluation of translational potential in photochemistry and photobiology Shiyong Wu
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Frontiers in Photobiology Part 1: Light-Matter Interactions Across Scales
Chair: TBD
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Frontiers in Photobiology Part 2
Chair: TBD
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Kendric C. Smith Symposium
Chair: TBD
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Molecules for Phototherapy and Bioimaging Part 1
Chair: Wenfang Sun
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Molecules for Phototherapy and Bioimaging Part 2
Chair: Wenfang Sun
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Ocular Photobiology and Vision
Chair: Beth Gaillard
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Optogenetics, Synthetic Biology
Chair: Ajith Karunarathne
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Photodynamic Therapy in Translation: Innovations in Technologies through Techniques
Chair: Theresa Busch
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Photopharmacology
Chair: Phoebe Glazer
May 17 Afternoon Photopharmacology 3:15 – 3:35 Light-activated MDM2 inhibitors: Toward spatiotemporal control in cancer therapy Sina Katharina Goetzfried 3:36 – 4:01 Ruthenium-based photoactivated chemotherapy for the treatment of cancer: recent developments Sylvestre Bonnet 4:02 – 4:27 Photoactivatable Platinum(IV) Complexes: Versatile Chemical Tools for Biomedical Applications Yaorong Zheng 4:28 – 4:48 Ruthenium photocaged CHIR99021 for robust stem cell differentiation Teresa Rapp 4:49 – 5:14 Selective targeting of proteins and pathways using photopharmacology Phoebe Glazer
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Photobiology Across the Visible Spectrum: Oxidative Stress, Skin Pigmentation, Clinical Responses, Photoprotection, Aging, and Photocarcinogenesis
Chairs: Eduardo Ruvolo, Indermeet Kohli
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Photosensitization Mechanisms and Photoreaction Pathways
Chair: Ryan McCulla
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Photothermal Therapy (PTT)
Chair: Emily Gawrys
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Structures and Mechanisms of Photoreceptors and Light-sensitive Proteins
Chair: Xiaojing Yang
May 18 Morning Structures and Mechanisms of Photoreceptors and Light-sensitive Proteins 9:05-9:35 Dynamics of mechanism of a dual function of DNA repair and signal transduction by CraCRY protein Dongping Zhong 9:35-10:05 Light-induced structural changes in B12-dependent photoreceptor CarH revealed by temperature-scan crystallography Zhong Ren 10:05-10:30 Coffee break 10:30-11:55 From femtoseconds to function: integrative spectroscopy to develop novel fast red reversible photoswitchable fluorescent proteins. Michel Sliwa 10:55-11:20 Energy transfer from phycobilisomes to photosystems and its regulation Jindong Zhao 11:20-11:40 Investigating the solvent specific spectral responses of carotenoids through resonance Raman spectroscopy Kaustavm Das 11:40-12:00 Molecular mechanisms of spectrum tuning in far-red photoreceptor Xiaojing Yang -
The Skin Cancer Epidemic: An Arizona Perspective on Innovative Scientific and Population Based Approaches to Address the Challenge
Chairs: Georg Wondrak, Clara Curiel-Lewandrowski
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Trainee Platform I
Chair: TBD
May 19 Morning Trainee Platform I 10:30 – 10:42 Heterogeneous oxygen dynamics during photodynamic therapy detected with real-time ultrasound-guided photoacoustic imaging for personalized dosimetry Andrew Langley 10:42 – 10:54 Cholesterol-Dependent Regulation of PHB-1 Nuclear Function and Self-Aggregation Following Solar UV Irradiation in Keratinocytes Zeinab Fayyaz 10:54 – 11:06 Investigating structure-activity relationships of photoactive metallodrugs as antimicrobials Gurleen Kaur 11:06 – 11:18 Synthesis and characterization of homoleptic oligothienyl-substituted Ir(III) and Ru(II) bis(terpyridine) complexes: photophysics and photodynamic therapeutic effects Kalara Develigoda Gamage 11:18 – 11:30 Synthesis and Characterization of Light-Triggered Metal Complexes for Cancer Treatment Dalton Lucas 11:30 – 11:42 Photochemistry and Mechanistic Studies of Diaryl Sulfondiimine Derivatives Paul Danyi 11:42 – 11:54 Light Transmission as an Indication for Response to Interstitial Photodynamic Therapy Chris Lawson 11:54 – 12:00 Judges Deliberation
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Trainee Platform II
Chair: TBD
May 19 Afternoon Trainee Platform II 3:15 – 3:27 Programmable Photo-Active CPC-like Surfactants as Environmentally Benign Alternatives to Cationic Antimicrobial Agents Balaka Ghosh 3:27 – 3:39 Optimizing the phototherapy effects of metallodrug photosensitizers for cancer treatment Ge Shi 3:39 – 3:51 Patterns in Polyphylla: shifts in coloration and pattern in response to climate change Colton Roberts-Zaffiro 3:51 – 4:03 Biocompatibility of Non-Aqueous Solvents with Rhodobacter sphaeroides Chromatophores Claudia Zonno 4:03 – 4:15 Photobiological Applications of Light-Activated Metallodrugs Alisher Talgatov 4:15 – 4:27 Expanding the NIR fluorophore toolbox: A general route to access polymethine-modified Cyanine 9 dyes for deep-tissue imaging Jared Head 4:27 – 4:39 Cyclic AMP Response Element-Binding Protein (CREB) as a novel biomarker for evaluating photoprotection of photoprotective agents in attenuating skin carcinogenesis Julianne Nayar 4:39 – 4:51 Comparative evaluation of perfluorocarbon core dependent nanodroplets for enhanced photodynamic therapy in 3D head and neck cancer spheroids Ronak Shethia 4:51 – 5:15 Judges Deliberation
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Translational Photodynamic Strategies: Immune Responses, Priming, and Therapeutic Synergy
Chair: Joe Huang
May 17 Morning Translational Photodynamic Strategies: Immune Responses, Priming, and Therapeutic Synergy 10:05 – 10:35 Image-guided photoimmunotherapy reveals immune priming and tumor–immune dynamics in preclinical models Bryan Spring 10:35 – 11:05 Photochemical Targeting of the Ovarian Cancer Lipidome: Docosahexaenoic Acid Sensitizes Ovarian Cancer Cells to Photodynamic Priming and Ferroptosis Marta Overchuk 11:05 – 12:00 Beyond Cytotoxicity: Photodynamic Priming to Disable Drug Efflux and Restore Therapeutic Response Huang Chiao Huang 12:00 – 12:30 Combination of vitamin D with photodynamic therapy for treatment of B16 malignant melanoma in mice Sanjay Anand 12:30 – 1:00 Targeted Organelle Localization-Induced Polymerization for Live-cell Imaging and Cancer Therapy Ja-Hyoung Ryu
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Ultrafast Dynamics in Photobiology
Chair: Carlos Crespo
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UVB-Induced DNA Damage, Repair, and Skin Carcinogenesis
Chair: Veronica Bahamondes Lorca
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UVC Germicidal Science
Chair: David Sliney
| May 17 Afternoon | Antimicrobial Photodynamic Therapy Part 1 | |
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| 3:15 – 3:35 | Structure–activity relationships in porphyrinoids for antimicrobial and anticancer photodynamic therapy | Janusz Dabrowski |
| 3:35 – 3:55 | Linking ligand architecture to antimicrobial efficacy in Ru(II)-based photosensitizers for Photodynamic Therapy | Maria Auset |
| 3:55 – 4:15 | Antimicrobial Photodynamic Inactivation with 2,3-Distyrylindoles | Alexander Kornienko |
| 4:15 – 4:35 | Comparative Photophysical and Photodynamic Inactivation of Aspergillus niger Spores and Staphylococcus aureus by Rutin- and Quercetin-Loaded Nanoemulsions | Cristia Villa |
| 4:35 – 4:55 | Exploring antimicrobial photodynamic therapy as a treatment option for complicated urinary tract infection | Chelsie Armbruster |
| 4:55 – 5:15 | Transition / Preparation for closing remarks |
| May 19 Afternoon | Antimicrobial Photodynamic Therapy Part 2 | |
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| 3:15 – 3:35 | Role of Bacterial Heterogeneity in Modulating ROS-Mediated Antimicrobial Phototherapy | Andres Durantini |
| 3:35 – 3:55 | Light-activated silver nanoparticles for inactivation of antibiotic-resistant bacteria and elimination of biofilms | Juan Vivero-Escoto |
| 3:55 – 4:15 | Engineering Titanium Dioxide Nanoparticles for Enhanced Antimicrobial Photodynamic Therapy of Biofilm-Associated Infections | Anna Cristina Samia |
| 4:15 – 4:35 | Structure–Function Insights into Amino-Flavylium Dyes for Antimicrobial Photodynamic Therapy | Patricia Correia |
| 4:35 – 5:15 | Moderated Discussion / Cross-Talk / Audience Q A |
| May 18 Afternoon | Frontiers I: Living Photonics: Light–Matter Interactions Across Scales | |
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| 3:15 – 3:35 | Illuminating ultraweak photon emission research for quantum nonlinear biophotonics | Nathan Babcock |
| 3:35 – 3:55 | Lanthanide-based complexes for bioimaging and singlet oxygen generation | Ana de Bettencourt-Dias |
| 3:55 – 4:15 | Photostability of therapeutic mAbs and ADCs under real-life light doses | Giorgia Miolo |
| 4:15 – 4:35 | Photosynthetic bacteria for light-driven energy production and environmental bioremediation | Rossella Labarile |
| 4:35 – 4:55 | Reflectin: a protein machine dynamically fine-tuning the color | Daniel Morse |
| 4:55 – 5:15 | Moderated Discussion / Cross-Talk / Audience Q&A |